The Mississippi River is the chief river of the largest river system in North America. Flowing entirely in the United States (though its drainage basin reaches into Canada), it rises in northern Minnesota and meanders slowly southwards for 2,530 miles (4,070 km) to the Mississippi River Delta at the Gulf of Mexico. With its many tributaries, the Mississippi's watershed drains all or parts of 31 US states between the Rocky and Appalachian Mountains and even reaches into southern Canada. The Mississippi ranks as the fourth longest and tenth largest river in the world. The river either borders or cuts through the states of Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana.

Native Americans lived along the Mississippi and its tributaries. Most were hunter-gatherers or herders, but some, such as the Mound builders, formed prolific agricultural societies. The arrival of Europeans in the 1500s changed the native way of life as first explorers, then settlers, ventured into the basin in increasing numbers. The river served first as barrier – forming borders for New Spain, New France, and the early United States – then as vital transportation artery and communications link. In the 19th century, during the height of Manifest Destiny, the Mississippi and several western tributaries, most notably the Missouri, formed pathways for pioneers partaking in the western expansion of the United States.

Formed from thick layers of this river's silt deposits, the Mississippi River Valley is one of the most fertile agricultural regions of the country, which resulted in the river's storied steamboat era. During the American Civil War, the Mississippi's capture by Union forces marked a turning point towards victory because of this very importance as a route of trade and travel, not least to the Confederacy. Because of substantial growth of cities and the larger ships and barges that have supplanted riverboats, the decades following the 1900s saw massive engineering works applied to the river system, such as the often in-combination construction of levees, locks and dams.

Since modern development of the basin began, the Mississippi has also seen its share of pollution and environmental problems – most notably large volumes of agricultural runoff, which has led to the Gulf of Mexico dead zone off the Delta.

en.wikipedia.org/wiki/Mississippi_River